Exacerbated COPD in Geriatric Patients at the “Camilo Cienfuegos” Provincial General Hospital

Authors

Keywords:

Disease Progression, Aged, Hospitalization, Chronic obstructive pulmonary disease

Abstract

Introduction: Chronic obstructive pulmonary disease exacerbation in elderly patients represents a critical event with high frailty and frequent polypharmacy, leading to a high risk of functional decline and hospitalization.

Objective: To analyze the behavior of exacerbated chronic obstructive pulmonary disease in elderly patients admitted to the Geriatrics Ward of Camilo Cienfuegos General Hospital.

Methods: A prospective, observational study was conducted at the institution. The sample consisted of 142 patients hospitalized for this condition during the study period who met the inclusion and exclusion criteria. The variables used were age, sex, risk factors, comorbidities, phenotype, clinical findings at admission, and discharge status. Descriptive statistics were used to calculate absolute and relative frequencies, the results of which were represented in distribution tables.

Results: 42.2 % were in the 70-79 age group, 59.2 % were men; viral infections predominated (64.8 %), 39.4 % were diabetic, and 38.1% suffered from cardiovascular disease and/or anxiety; chronic bronchitic exacerbation predominated (45.1 %), polypnea (95.1 %) and cough (92.9 %) were the most frequent symptoms; infections and severe malnutrition (69.1 %) were the most reported complications; 73.9 % of patients were discharged alive.

Conclusions: Diabetic men aged 70-79 years predominated, with viral infections, cough, and polypnea, and the chronic bronchitic exacerbation phenotype. Their main complication was delirium, and the majority survived without sequelae.

Downloads

Download data is not yet available.

Author Biographies

Yuniel Abreu Hernández, Universidad de Ciencias Médicas. Hospital General Camilo Cienfuegos. Servicio de Medicina Interna. Sancti-Spíritus. Cuba.

Especialista de Segundo Grado en Medicina General Integral y Medicina Interna. Máster en Sexología Clínica. Profesor Auxiliar. Investigador Agregado. 

Daimara Barrera León, Universidad de Ciencias Médicas. Hospital Camilo Cienfuegos. Servicio de Geriatría. Sancti-Spíritus. Cuba.

Especialista de Primer Grado en Geriatría y Gerontología. Profesor Asistente. 

Yamil Fidel García Guevara, Universidad de Ciencias Médicas. Hospital General Camilo Cienfuegos. Servicio de Medicina Interna. Sancti-Spíritus. Cuba.

Especialista de Primer Grado en Medicina General Integral y Medicina Interna. Profesor Instructor. 

Jorge Luis Lorente Montiel, Universidad de Ciencias Médicas. Sancti-Spíritus. Cuba.

Estudiante de tercer año de la carrera de medicina. 

References

1. Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease (2023 Report). 2023 [Acceso: 15/05/2025]. Available from: https://goldcopd.org/2023-gold-report-2/

2. Hanania NA, Sharma G, Sharafkhaneh A. COPD in the Elderly: A Review of the Current Literature. Curr Opin Pulm Med. 2021 [Acceso: 22/05/2025];27(3):208-216. Available from: https://journals.lww.com/co-pulmonarymedicine/Abstract/2021/05000/COPD_in_the_elderly__a_review_of_the_current.8.aspx

3. Martínez CH, Diaz AA, Parulekar AD, Rennard SI, Hansel NN, Curtis JL, et al. Age-Related Differences in Health-Related Quality of Life in COPD: An Analysis of the COPDGene and SPIROMICS Cohorts. Chest. 2021 [Acceso 10/06/2025];159(6):2209-18. Available from: https://journal.chestnet.org/article/S0012-3692(20)35325-7/fulltext

4. Scarlata S, Finamore P, Laudisio A, Antonelli-Incalzi R. Association of Geriatric Conditions with the Risk of Exacerbations in Elderly Patients with COPD: A Population-Based Cohort Study. Eur J Intern Med. 2022 [Acceso 05/07/2025];96:76-82. Available from: https://www.ejinme.com/article/S0953-6205(21)00367-5/fulltext

5. Álvarez-Gutiérrez FJ, Miravitlles M, Calle M, Gobartt-Vázquez E, Castelao EF, Soler-Cataluña JJ, et al. Impact of Exacerbations on Disease Outcomes and Management in COPD: Focus on the Elderly. Int J Chron Obstruct Pulmon Dis. 2023 [Acceso 18/05/2025];18:499-511. Available from: https://www.dovepress.com/impact-of-exacerbations-on-disease-outcomes-and-management-in-copd-foc-peer-reviewed-fulltext-article-COPD

6. Suissa S, Dell'Aniello S, Ernst P. Long-term Natural History of Chronic Obstructive Pulmonary Disease: Severe Exacerbations and Mortality. Thorax. 2022 [Acceso: 25/06/2025];77(11):1084-1091. Available from: https://thorax.bmj.com/content/77/11/1084

7. Gerayeli FV, Milne S, Cheung C, Sin DD. COPD and the Risk of Poor Outcomes in COVID-19: A Systematic Review and Meta-Analysis. EClinicalMedicine. 2021 [Acceso 12/07/2025];33:100789. Available from: https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(21)00156-3/fulltext

8. Higham A, Mathioudakis A, Vestbo J, Singh D. COVID-19 and COPD: A Narrative Review of the Basic Science and Clinical Outcomes. Eur Respir Rev. 2020 [Acceso: 30/05/2025];29(158):200199. Available from: https://err.ersjournals.com/content/29/158/200199

9. Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease (2023 Report). 2023 [Acceso: 15/05/2025]. Available from: https://goldcopd.org/2023-gold-report-2/

10. Ministerio de Salud Pública (MINSAP). Anuario Estadístico de Salud 2022. La Habana: MINSAP; 2023 [Acceso: 14/06/2025]. Disponible en: http://www.sld.cu/anuario-estadistico-de-cuba

11. World Medical Association. WMA Declaration of Helsinki - Ethical Principles for Medical Research Involving Human Subjects. 2024 [Acceso: 10/05/2025]. Available from: https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects/

12. Salabert Tortoló I, Alfonso Guerra D, Alfonso Salabert I, Mestre Cárdenas VA, Valdés Gazmuri I, Drake García O. Factores de riesgo en la enfermedad pulmonar obstructiva crónica y su enfoque con los niveles de intervención de salud. Rev médica electrón. 2018 [Acceso: 21/09/2025];40(5):1629–46. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1684-18242018000501629

13. Martinez-Sanchez LM, Lopez Lopez L, Roldan-Tabares MD, Herrera-Almanza L, Lobo-Salas YF, Arboleda-Rojas M, et al. Caracterización clínica y epidemiológica de la enfermedad pulmonar obstructiva crónica. Repert Med Cir. 2023 [Acceso: 21/09/2025];33(2):158-162. Disponible en: https://revistas.fucsalud.edu.co/index.php/repertorio/article/view/1455

14. Hernández YA, León DB, Reyes AH, Luis ÁLZ. Comportamiento clínico-epidemiológico de la enfermedad pulmonar obstructiva crónica en el Hospital General Provincial Camilo Cienfuegos. Med Gen Fam. 2024 [Acceso: 21/09/2025];13(1):3-10. Disponible en: https://dialnet.unirioja.es/servlet/articulo?codigo=9399637

15. Ozoh OB, Dede SK, Ekete OA, Ojo OO, Dania MG. Risk factors for chronic obstructive pulmonary disease (COPD) in a tertiary health institution in Lagos. Niger J Clin Pract. 2021 [Acceso: 21/09/2025];24(5):739-47. Available from: https://www.njcponline.com/article.asp?issn=1119-3077;year=2021;volume=24;issue=5;spage=739;epage=747;aulast=Ozoh

16. González Rodríguez R, Barcón Díaz L. Caracterización clínico-epidemiológica de pacientes con enfermedad pulmonar obstructiva crónica reagudizada. Arch méd Camagüey. 2018 [Acceso: 21/09/2025];22(3):292–302. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1025-02552018000300005

17. Miravitlles M, Calle M, Molina J, Almagro P, Gómez JT, Trigueros JA, et al. Exacerbations of chronic obstructive pulmonary disease in the elderly: a propensity score matched comparison of clinical characteristics and outcomes. Eur Respir J. 2022 [Acceso: 25/09/2025];59(4):2101143. Available from: https://erj.ersjournals.com/content/59/4/2101143

18. Elías Sierra R, Elías Armas KS, Choo Ubals T, Bordelois Abdo MS. Factores relacionados con la letalidad de la enfermedad pulmonar obstructiva crónica exacerbada. Rev Cubana Med [Internet]. 2022 [Acceso 25/09/2025];61(4):e2140. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75232022000400014

19. De Abajo Larriba AB, Méndez Rodríguez E, González-Gallego J, Capón Álvarez J, Díaz Rodríguez Á, Peleteiro Cobo B, et al. Estimación de la prevalencia de los fenotipos en pacientes con enfermedad pulmonar obstructiva crónica: estudio ADEPOCLE. Nutr Hosp [Internet]. 2017 [Acceso: 25/09/2025];34(1):180–5. Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112017000100027

20. Almagro P, Martínez-Cambor P, Sellarés J, Heredia JL, Torres F, Llor C. Clinical Characteristics and Outcomes of Elderly Patients with COPD Exacerbations. Arch Bronconeumol. 2020 [Acceso: 25/09/2025];56(8):499-505. Available from: https://www.archbronconeumol.org/en-clinical-characteristics-outcomes-elderly-patients-avance-S030028962030158X

21. González-Méndez A, Hernández-Reyes A, Fernández-Coral RF, Regalado-López RM, Morell-León LR, Conde-Fernández BD. Caracterización de pacientes con enfermedad pulmonar obstructiva crónica en el Hospital General Provincial de Sancti Spíritus. Arch méd Camagüey [Internet]. 2023 [Acceso: 25/09/2025]; 27:e9779. Disponible en: https://revistaamc.sld.cu/index.php/amc/article/view/9779

22. Rodríguez Concepción JP, Conde Fernández BD, Valdés Rodríguez MF, Cepero Rodríguez I, Hidalgo Mesa CJ, Valdés Rodríguez AM, et al. Características clínicas de pacientes con exacerbación de la enfermedad pulmonar obstructiva crónica. Rev. cuba. med. mil [Internet]. 15 de diciembre de 2022 [Acceso: 25/09/ 2025];51(4):e02202476. Disponible en: https://revmedmilitar.sld.cu/index.php/mil/article/view/2476

23. Núñez-Cortés R, López-López L, Lucero-Ulloa C, Painel-Cruz C, Becerra-Muñoz V, Martínez-Arnau FM. Comorbidities and systemic effects of chronic obstructive pulmonary disease in the elderly: a scoping review. Rev Esp Geriatr Gerontol. 2023 [Acceso: 25/09/2025];58(5):101399. Available from: https://www.elsevier.es/es-revista-revista-espanola-geriatria-gerontologia-124-avance-comorbidities-systemic-effects-chronic-obstructive-S0211139X23000669

24. García Gómez A, Ramírez Cruz N, Agüero Carbonell Y, Hernández Torres A, Massó Vicet Y, Martínez Llano Y. Caracterización de pacientes con enfermedad pulmonar obstructiva crónica en la unidad de cuidados intensivos. Rev Cuba Med Mil [Internet]. 2021 [Acceso 25/09/2025];50(4):e0244. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-65572021000400004

Published

2026-01-05

How to Cite

1.
Abreu Hernández Y, Barrera León D, García Guevara YF, Lorente Montiel JL. Exacerbated COPD in Geriatric Patients at the “Camilo Cienfuegos” Provincial General Hospital. GeroInfo [Internet]. 2026 Jan. 5 [cited 2026 Feb. 2];21:e343. Available from: https://revgeroinfo.sld.cu/index.php/gerf/article/view/343

Issue

Section

Artículo de Investigación